Green and diastereoselective synthesis of trans-3-(5-methylisoxazol-3-yl)-3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazines
نویسندگان
چکیده مقاله:
Reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields.
منابع مشابه
green and diastereoselective synthesis of trans-3-(5-methylisoxazol-3-yl)-3,4-dihydro-2h-naphtho[2,3-e][1,3]oxazines
reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-sio2/hclo4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1h-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1h-pyrazol-5-ol derivatives in high yields.
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3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activi...
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3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activi...
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عنوان ژورنال
دوره 4 شماره 3
صفحات 133- 141
تاریخ انتشار 2014-09-01
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